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hydrogen peroxide

Hydrogen peroxide is a compound that has a strong oxidation effect, and its chemical formula is H₂O₂. It is used in gasified form as an antiseptic for laboratory equipment, including safety cabinets and isolators used for manufacturing regenerative medical products. It is also used in buildings and facilities with clean rooms to reduce the number of microorganisms to a pre-specified level.
In cell manufacturing facilities for products such as regenerative medicine, it is necessary to reduce the number of microorganisms attached to consumables and equipment to be brought into the clean area or aseptic operation area to the pre-defined degree of cleanliness appropriate for the intended use. Decontamination is performed with reagents such as hydrogen peroxide gas, and disinfection by wiping with a mixture of hydrogen peroxide and peracetic acid or 70% ethanol.
In addition, during changeovers in the manufacturing process, it is required to disinfect or decontaminate aseptic operation areas and bio-clean rooms, with gasified hydrogen peroxide being effective in doing so. General instruments may not be compatible with decontamination with gases such as hydrogen peroxide, and the residual gas on the instruments' surface after decontamination may adversely affect cells in culture. Therefore, when decontaminating with gases such as hydrogen peroxide, it is necessary to select suitable materials and instruments.