OoC・MPS
(organ-on-a-chip・microphysiological systems)
Organ-on-Chip is a new in vitro evaluation system that mimics the biological environment on a chip that is smaller than the size of a palm. It is called in many different names, but recently microphysiological systems (MPS) is used more often. It was made possible by cell culture technology, cell evaluation technology and microfluidic device technology and is still fast-evolving. Organs have their own specific cells and structures, so some MPS may mimic part of organs. There is a variety of other types and purposes. For instance, some aim at interaction of individual organs such as the small intestine and liver, and some are derived from individuals. In the field of drug discovery, its usefulness in pharmacokinetics and toxicity evaluation is attracting attention, and it is expected as an alternative to animal testing.
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