neural stem cell
Neural stem cells (NSCs) have the ability to self-renew and differentiate into multiple types of neuronal and glial cell types in the brain and spinal cord. Cell morphology changes dynamically during the process of differentiation from pluripotent stem cell to NSC.
The release of signaling molecules from gastrointestinal organizer cells determines the cell fate in the outer leaflet region, resulting in neuronal differentiation. In this process, inhibition of bone morphogenetic protein (BMP) signaling and activation of fibroblast growth factor (FGF) signaling are important for neuronal fate commitment.
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